{"id":2520,"date":"2025-01-16T10:26:17","date_gmt":"2025-01-16T01:26:17","guid":{"rendered":"https:\/\/pf-form.kek.jp\/sbrc\/?p=2520"},"modified":"2025-01-16T10:26:17","modified_gmt":"2025-01-16T01:26:17","slug":"seminar21","status":"publish","type":"post","link":"https:\/\/pf-form.kek.jp\/sbrc\/seminar21\/","title":{"rendered":"SBRC International Cryo-EM Seminar No.21"},"content":{"rendered":"\n<p class=\"has-medium-font-size\"><\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<h2 class=\"wp-block-heading\">\u201c<strong>Structural Biology in Industry&nbsp;\u2013&nbsp;Proteros overview<\/strong>\u201d<\/h2>\n<\/blockquote>\n\n\n\n<p> _<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Date and Time<\/h2>\n\n\n\n<p style=\"font-size:25px\">5:00 PM &#8211; 6:30 PM Wednesday, January 22<sup>th<\/sup>, 2025<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Location<\/h2>\n\n\n\n<p style=\"font-size:25px\">Online (Zoom)<\/p>\n\n\n\n<p><\/p>\n\n\n<hr \/>\n\n\n<h2 class=\"wp-block-heading\" style=\"font-size:30px\">Speakers:<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\" style=\"font-size:28px\">Eva Cunha, PhD<\/h2>\n\n\n<div class=\"wp-block-image is-resized\">\n<figure class=\"alignleft size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"155\" height=\"204\" src=\"https:\/\/pf-form.kek.jp\/sbrc\/wp-content\/uploads\/sites\/39\/2025\/01\/Eva-Cunha-PhD.jpg\" alt=\"\" class=\"wp-image-2521\" style=\"aspect-ratio:0.8407310704960835;width:228px;height:auto\" \/><\/figure>\n<\/div>\n\n\n<p><strong>Profile:<\/strong><br>2006 Master (Bioinformatics), University of Lisbon, Portugal <br>2013 Ph.D. (Biophysics), Jonhs Hopkins University, USA <br>2013-2015 Postdoctoral Researcher with Dr. N. Abrescia, CIC-Biogune, Spain <br>2016-2018 Postdoctoral Researcher with Dr. W. Kuhlbrandt, Max-Planck-Institute for Biophysics, Germany <br>2018-2021 Researcher, University of Oslo, Norway <br>2021-2022 Principal Investigator, University of Oslo, Norway <br>2022-2023 Director for cryoEM, Proteros Biostructures, Germany <br>2024-Present Department Head and BU co-head for cryoEM, Proteros Biostructures, Germany<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" style=\"font-size:28px\">Stephan Krapp, PhD<\/h2>\n\n\n<div class=\"wp-block-image is-resized\">\n<figure class=\"alignleft size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"186\" height=\"259\" src=\"https:\/\/pf-form.kek.jp\/sbrc\/wp-content\/uploads\/sites\/39\/2025\/01\/Stephan-Krapp-PhD.jpg\" alt=\"\" class=\"wp-image-2523\" style=\"aspect-ratio:0.8407310704960835;width:228px;height:auto\" \/><\/figure>\n<\/div>\n\n\n<p><strong>Profile:<\/strong><br>1997 Master of Biochemistry, Imperial College, UK \/ University of Bayreuth, Germany <br>2002 Ph.D. in Protein Crystallography, Max-Planck-Institute of Biochemistry, Martinsried, Germany (Prof. Dr. Robert Huber) <br>2003 Research scientist and project manager at Proteros Biostructures, Martinsried, Germany <br>2010 Department Head of Structural Biology at Proteros Biostructures, Martinsried, Germany <br>2022 \u2013 present: Business Unit Head x-ray crystallography and co-Department head x-ray crystallography at Proteros Biostructures, Martinsried, Germany<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Abstract<\/h2>\n\n\n\n<p>Proteros offers cutting-edge cryo-electron microscopy (cryoEM) and x-ray crystallography services tailored to accelerate drug discovery by providing high-resolution structural insights into challenging pharmaceutical targets. Our platform integrates state-of-the-art cryoEM and x-ray instrumentation, proprietary workflows, and deep expertise in structure determination to deliver actionable data for small-molecule and biologics programs.<\/p>\n\n\n\n<p>Proteros specializes in resolving protein structures, protein-ligand complexes, and multi-protein assemblies with precision, even for challenging targets like membrane proteins. By enabling atomic resolution insights, our services empower researchers to drive structure-based drug design, optimize lead compounds, and elucidate mechanisms of action. This talk will highlight Proteros\u2019 streamlined processes, success stories, and how our structural biology capabilities bridge the gap between molecular structures and therapeutic breakthroughs. Case studies will include GPCR\u00b4s (e.g. GLP1R), ion channels (e.g. Kv.1.3) Kinases (e.g. TAK1, cRAF-14-3-3) and others.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-css-opacity is-style-dots\" \/>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-white-color has-cyan-bluish-gray-background-color has-text-color has-background\"><a href=\"https:\/\/pf-form.kek.jp\/sbrc\/registration_for_international_seminar\/\" data-type=\"link\" data-id=\"https:\/\/pf-form.kek.jp\/sbrc\/registration_for_international_seminar\/\">Click here to apply<\/a><\/h2>\n","protected":false},"excerpt":{"rendered":"<p>\u201cStructural Biology in Industry&nbsp;\u2013&nbsp;Proteros overview\u201d _ Date and Time 5:00 PM &#8211; 6:30 PM Wednesd [&hellip;]<\/p>\n","protected":false},"author":26,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-2520","post","type-post","status-publish","format-standard","hentry","category-kek-cryoem"],"_links":{"self":[{"href":"https:\/\/pf-form.kek.jp\/sbrc\/wp-json\/wp\/v2\/posts\/2520","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pf-form.kek.jp\/sbrc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pf-form.kek.jp\/sbrc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pf-form.kek.jp\/sbrc\/wp-json\/wp\/v2\/users\/26"}],"replies":[{"embeddable":true,"href":"https:\/\/pf-form.kek.jp\/sbrc\/wp-json\/wp\/v2\/comments?post=2520"}],"version-history":[{"count":16,"href":"https:\/\/pf-form.kek.jp\/sbrc\/wp-json\/wp\/v2\/posts\/2520\/revisions"}],"predecessor-version":[{"id":2541,"href":"https:\/\/pf-form.kek.jp\/sbrc\/wp-json\/wp\/v2\/posts\/2520\/revisions\/2541"}],"wp:attachment":[{"href":"https:\/\/pf-form.kek.jp\/sbrc\/wp-json\/wp\/v2\/media?parent=2520"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pf-form.kek.jp\/sbrc\/wp-json\/wp\/v2\/categories?post=2520"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pf-form.kek.jp\/sbrc\/wp-json\/wp\/v2\/tags?post=2520"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}